Drug interactions
Maraviroc + Procarbazine
Severity: Minor
Maraviroc and Procarbazine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Maraviroc can cause postural hypotension, and procarbazine with its MAO inhibiting activity may also affect blood pressure. Together they may increase dizziness, falls or syncope. The evidence is limited.
What this interaction means in plain words
Maraviroc and Procarbazine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Maraviroc belongs to Anti Virals; Procarbazine belongs to Oncology.
Why it happens
Additive blood pressure lowering effects; no pharmacokinetic mechanism is established.
What to do
Counsel the patient about orthostatic symptoms and check blood pressure when starting the combination. Adjust therapy if symptomatic hypotension occurs.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Procarbazine
- Adenovirus types 4 and 7 live + Procarbazine Contraindicated
- Amitriptyline + Procarbazine Contraindicated
- Amoxapine + Procarbazine Contraindicated
- Atomoxetine + Procarbazine Contraindicated
- Bcg vaccine live + Procarbazine Contraindicated
- Brimonidine + Procarbazine Contraindicated
Other interactions of Maraviroc
- Amobarbital + Maraviroc Major
- Apalutamide + Maraviroc Major
- Carbamazepine + Maraviroc Major
- Clarithromycin + Maraviroc Major
- Efavirenz + Maraviroc Major
- Enzalutamide + Maraviroc Major
Frequently asked questions
Can I take Maraviroc with Procarbazine?
MediHelp rates the interaction as minor. Maraviroc and Procarbazine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Maraviroc can cause postural hypotension, and procarbazine with its MAO inhibiting activity may also affect blood pressure. Together they may increase dizziness, falls or syncope. The evidence is limited.
How serious is the interaction between Maraviroc and Procarbazine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Counsel the patient about orthostatic symptoms and check blood pressure when starting the combination. Adjust therapy if symptomatic hypotension occurs.
What other medicines interact with Procarbazine?
MediHelp also lists interactions of Procarbazine with, for example, Adenovirus types 4 and 7 live, Amitriptyline, Amoxapine. The full list is on the Procarbazine page.
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