Drug interactions
Maraviroc + Sertraline
Severity: Minor
Maraviroc and Sertraline: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Maraviroc is a CYP3A4 substrate with little inhibitory effect on CYP enzymes, so it is not expected to meaningfully change sertraline levels. Any clinical interaction is unlikely.
What this interaction means in plain words
Maraviroc and Sertraline have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Maraviroc belongs to Anti Virals; Sertraline belongs to Central Nervous System.
Why it happens
No established mechanism; maraviroc does not significantly inhibit CYP3A4.
What to do
No dose adjustment is expected to be needed; monitor clinical response routinely.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Sertraline
- Isocarboxazid + Sertraline Contraindicated
- Methylene blue + Sertraline Contraindicated
- Phenelzine + Sertraline Contraindicated
- Pimozide + Sertraline Contraindicated
- Selegiline transdermal + Sertraline Contraindicated
- Selegiline + Sertraline Contraindicated
Other interactions of Maraviroc
- Amobarbital + Maraviroc Major
- Apalutamide + Maraviroc Major
- Carbamazepine + Maraviroc Major
- Clarithromycin + Maraviroc Major
- Efavirenz + Maraviroc Major
- Enzalutamide + Maraviroc Major
Frequently asked questions
Can I take Maraviroc with Sertraline?
MediHelp rates the interaction as minor. Maraviroc and Sertraline have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Maraviroc is a CYP3A4 substrate with little inhibitory effect on CYP enzymes, so it is not expected to meaningfully change sertraline levels. Any clinical interaction is unlikely.
How serious is the interaction between Maraviroc and Sertraline?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose adjustment is expected to be needed; monitor clinical response routinely.
What other medicines interact with Sertraline?
MediHelp also lists interactions of Sertraline with, for example, Isocarboxazid, Methylene blue, Phenelzine. The full list is on the Sertraline page.
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