Drug interactions
Methamphetamine + Nabilone
Severity: Moderate
Methamphetamine and Nabilone: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Nabilone is sedating and can cause tachycardia and mood changes, while methamphetamine is a stimulant that raises heart rate and blood pressure. Together the cardiovascular stimulation may be additive and the sedative and stimulant effects may mask each other, making the net effect unpredictable.
What this interaction means in plain words
Methamphetamine and Nabilone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Methamphetamine belongs to Central Nervous System; Nabilone belongs to Gastrointestinal Tract.
Why it happens
Opposing CNS effects with additive sympathomimetic cardiovascular effects such as tachycardia.
What to do
Monitor heart rate, blood pressure and mental status, and avoid relying on one drug to offset the effects of the other. Reassess the need for the combination if tachycardia, anxiety or psychosis occurs.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Nabilone
Other interactions of Methamphetamine
- Isocarboxazid + Methamphetamine Contraindicated
- Linezolid + Methamphetamine Contraindicated
- Methamphetamine + Phenelzine Contraindicated
- Methamphetamine + Procarbazine Contraindicated
- Methamphetamine + Rasagiline Contraindicated
- Methamphetamine + Safinamide Contraindicated
Frequently asked questions
Can I take Methamphetamine with Nabilone?
MediHelp rates the interaction as moderate. Methamphetamine and Nabilone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Nabilone is sedating and can cause tachycardia and mood changes, while methamphetamine is a stimulant that raises heart rate and blood pressure. Together the cardiovascular stimulation may be additive and the sedative and stimulant effects may mask each other, making the net effect unpredictable.
How serious is the interaction between Methamphetamine and Nabilone?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor heart rate, blood pressure and mental status, and avoid relying on one drug to offset the effects of the other. Reassess the need for the combination if tachycardia, anxiety or psychosis occurs.
What other medicines interact with Nabilone?
MediHelp also lists interactions of Nabilone with, for example, Alfentanil, Amobarbital, Belladonna and opium. The full list is on the Nabilone page.
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