Drug interactions
Micafungin + Tazemetostat
Severity: Minor
Micafungin and Tazemetostat: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Tazemetostat is metabolized by CYP3A4, and micafungin may weakly inhibit this enzyme. A modest increase in tazemetostat exposure is theoretically possible but not shown clinically.
What this interaction means in plain words
Micafungin and Tazemetostat have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Micafungin belongs to Anti Fungals; Tazemetostat belongs to Miscellaneous.
Why it happens
Possible weak CYP3A4 inhibition by micafungin reducing tazemetostat clearance.
What to do
No dose adjustment is required; monitor for tazemetostat adverse effects such as cytopenias and fatigue.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Micafungin
- Lomitapide + Micafungin Moderate
- Micafungin + Saccharomyces boulardii Moderate
- Micafungin + Sirolimus Moderate
- Avapritinib + Micafungin Minor
- Finerenone + Micafungin Minor
- Isavuconazonium + Micafungin Minor
Other interactions of Tazemetostat
Frequently asked questions
Can I take Micafungin with Tazemetostat?
MediHelp rates the interaction as minor. Micafungin and Tazemetostat have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Tazemetostat is metabolized by CYP3A4, and micafungin may weakly inhibit this enzyme. A modest increase in tazemetostat exposure is theoretically possible but not shown clinically.
How serious is the interaction between Micafungin and Tazemetostat?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose adjustment is required; monitor for tazemetostat adverse effects such as cytopenias and fatigue.
What other medicines interact with Micafungin?
MediHelp also lists interactions of Micafungin with, for example, Lomitapide, Saccharomyces boulardii, Sirolimus. The full list is on the Micafungin page.
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