Drug interactions
Minocycline + Porfimer
Severity: Moderate
Minocycline and Porfimer: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both minocycline and porfimer can cause photosensitivity. Taking them together may increase the risk or severity of phototoxic skin reactions such as sunburn-like erythema and blistering after light exposure.
What this interaction means in plain words
Minocycline and Porfimer can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Minocycline belongs to Anti Bacterial; Porfimer belongs to Miscellaneous.
Why it happens
Additive phototoxic effects of a photosensitizing tetracycline and a photodynamic therapy agent.
What to do
Counsel the patient to strictly avoid sunlight and bright indoor light for the period specified in the porfimer labeling. Consider holding minocycline or choosing a non-photosensitizing antibiotic during that period.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Minocycline
- Acitretin + Minocycline Contraindicated
- Isotretinoin + Minocycline Contraindicated
- Cholera vaccine + Minocycline Major
- Methoxyflurane + Minocycline Major
- Minocycline + Palovarotene Major
- Minocycline + Pexidartinib Major
Other interactions of Porfimer
Frequently asked questions
Can I take Minocycline with Porfimer?
MediHelp rates the interaction as moderate. Minocycline and Porfimer can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both minocycline and porfimer can cause photosensitivity. Taking them together may increase the risk or severity of phototoxic skin reactions such as sunburn-like erythema and blistering after light exposure.
How serious is the interaction between Minocycline and Porfimer?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Counsel the patient to strictly avoid sunlight and bright indoor light for the period specified in the porfimer labeling. Consider holding minocycline or choosing a non-photosensitizing antibiotic during that period.
What other medicines interact with Minocycline?
MediHelp also lists interactions of Minocycline with, for example, Acitretin, Isotretinoin, Cholera vaccine. The full list is on the Minocycline page.
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