Drug interactions
moxifloxacin + sotalol
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Overview
Additive QT prolongation → torsades risk.
Mechanism of action
Additive IKr blockade.
Clinical management
Avoid co-use; choose non-QT-prolonging antibiotic.
Drug reference
References
Frequently asked questions
Can I take moxifloxacin with sotalol?
The interaction is rated: Major. Additive QT prolongation → torsades risk.
How serious is the interaction between moxifloxacin and sotalol?
The interaction is rated: Major. Evidence level: High.
How is the interaction between moxifloxacin and sotalol managed?
Avoid co-use; choose non-QT-prolonging antibiotic.
Why do moxifloxacin and sotalol interact?
Additive IKr blockade.
Full monographs, dosing and an interaction checker in the MediHelp app
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