Drug interactions
Nifedipine + Porfimer
Severity: Minor
Nifedipine and Porfimer: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Calcium channel blockers have been reported to possibly reduce the photodynamic effect of porfimer by affecting vascular responses in treated tissue. The clinical importance is uncertain.
What this interaction means in plain words
Nifedipine and Porfimer have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Nifedipine belongs to Cardiovascular; Porfimer belongs to Miscellaneous.
Why it happens
Possible reduction of photodynamic vascular damage; mechanism not established.
What to do
Be aware that therapeutic response to photodynamic therapy may be reduced, and review the need for nifedipine around treatment if response is inadequate.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Nifedipine
Other interactions of Porfimer
Frequently asked questions
Can I take Nifedipine with Porfimer?
MediHelp rates the interaction as minor. Nifedipine and Porfimer have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Calcium channel blockers have been reported to possibly reduce the photodynamic effect of porfimer by affecting vascular responses in treated tissue. The clinical importance is uncertain.
How serious is the interaction between Nifedipine and Porfimer?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Be aware that therapeutic response to photodynamic therapy may be reduced, and review the need for nifedipine around treatment if response is inadequate.
What other medicines interact with Nifedipine?
MediHelp also lists interactions of Nifedipine with, for example, Amifostine, Amlodipine-benazepril, Apalutamide. The full list is on the Nifedipine page.
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