Drug interactions
Nitazoxanide + Piroxicam
Severity: Minor
Nitazoxanide and Piroxicam: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Nitazoxanide's active metabolite is highly protein bound and could theoretically displace other highly bound drugs such as piroxicam. Clinically meaningful effects have not been established.
What this interaction means in plain words
Nitazoxanide and Piroxicam have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Nitazoxanide belongs to Anti Bacterial; Piroxicam belongs to Musculoskeletal.
Why it happens
Theoretical competition for plasma protein binding sites.
What to do
No action is generally required. Monitor for increased NSAID adverse effects if both are used together.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Piroxicam
- Ketorolac intranasal + Piroxicam Contraindicated
- Ketorolac + Piroxicam Contraindicated
- Aceclofenac + Piroxicam Major
- Acemetacin + Piroxicam Major
- Acetylsalicylic acid + Piroxicam Major
- Alteplase + Piroxicam Major
Other interactions of Nitazoxanide
Frequently asked questions
Can I take Nitazoxanide with Piroxicam?
MediHelp rates the interaction as minor. Nitazoxanide and Piroxicam have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Nitazoxanide's active metabolite is highly protein bound and could theoretically displace other highly bound drugs such as piroxicam. Clinically meaningful effects have not been established.
How serious is the interaction between Nitazoxanide and Piroxicam?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No action is generally required. Monitor for increased NSAID adverse effects if both are used together.
What other medicines interact with Piroxicam?
MediHelp also lists interactions of Piroxicam with, for example, Ketorolac intranasal, Ketorolac, Aceclofenac. The full list is on the Piroxicam page.
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