Drug interactions
Omeprazole + Triclabendazole
Severity: Minor
Omeprazole and Triclabendazole: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Triclabendazole and its metabolites inhibit CYP2C19 to some degree and may raise omeprazole concentrations. The clinical consequence is usually small given omeprazole's wide safety margin.
What this interaction means in plain words
Omeprazole and Triclabendazole have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Omeprazole belongs to Gastrointestinal Tract; Triclabendazole belongs to Anti Parasitic.
Why it happens
Inhibition of CYP2C19 reduces omeprazole clearance.
What to do
No routine adjustment is needed; monitor for omeprazole adverse effects with prolonged high-dose use.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Omeprazole
- Mavacamten + Omeprazole Contraindicated
- Omeprazole + Rilpivirine Contraindicated
- Acalabrutinib + Omeprazole Major
- Atazanavir + Omeprazole Major
- Citalopram + Omeprazole Major
- Clopidogrel + Omeprazole Major
Other interactions of Triclabendazole
Frequently asked questions
Can I take Omeprazole with Triclabendazole?
MediHelp rates the interaction as minor. Omeprazole and Triclabendazole have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Triclabendazole and its metabolites inhibit CYP2C19 to some degree and may raise omeprazole concentrations. The clinical consequence is usually small given omeprazole's wide safety margin.
How serious is the interaction between Omeprazole and Triclabendazole?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine adjustment is needed; monitor for omeprazole adverse effects with prolonged high-dose use.
What other medicines interact with Omeprazole?
MediHelp also lists interactions of Omeprazole with, for example, Mavacamten, Rilpivirine, Acalabrutinib. The full list is on the Omeprazole page.
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