Drug interactions
Oxaliplatin + Ozanimod
Severity: Minor
Oxaliplatin and Ozanimod: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Ozanimod can cause transient heart rate slowing and conduction effects, and oxaliplatin has been associated with QT prolongation. Bradycardia may increase the risk of QT-related arrhythmia, although the combined risk is largely theoretical.
What this interaction means in plain words
Oxaliplatin and Ozanimod have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Oxaliplatin belongs to Oncology; Ozanimod belongs to Central Nervous System.
Why it happens
Possible additive cardiac effects: sphingosine receptor-mediated bradycardia with oxaliplatin-related QT prolongation.
What to do
Check baseline ECG before starting ozanimod and monitor heart rate and electrolytes during oxaliplatin therapy. Use extra monitoring if the patient has other QT risk factors.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Oxaliplatin
- Adenovirus types 4 and 7 live + Oxaliplatin Contraindicated
- Bcg vaccine live + Oxaliplatin Contraindicated
- Influenza virus vaccine quadrivalent intranasal + Oxaliplatin Contraindicated
- Measles mumps and rubella vaccine live + Oxaliplatin Contraindicated
- Measles mumps and rubella vaccine + Oxaliplatin Contraindicated
- Measles mumps rubella and varicella vaccine live + Oxaliplatin Contraindicated
Other interactions of Ozanimod
- Isocarboxazid + Ozanimod Contraindicated
- Linezolid + Ozanimod Contraindicated
- Ozanimod + Phenelzine Contraindicated
- Ozanimod + Procarbazine Contraindicated
- Ozanimod + Rasagiline Contraindicated
- Ozanimod + Safinamide Contraindicated
Frequently asked questions
Can I take Oxaliplatin with Ozanimod?
MediHelp rates the interaction as minor. Oxaliplatin and Ozanimod have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Ozanimod can cause transient heart rate slowing and conduction effects, and oxaliplatin has been associated with QT prolongation. Bradycardia may increase the risk of QT-related arrhythmia, although the combined risk is largely theoretical.
How serious is the interaction between Oxaliplatin and Ozanimod?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check baseline ECG before starting ozanimod and monitor heart rate and electrolytes during oxaliplatin therapy. Use extra monitoring if the patient has other QT risk factors.
What other medicines interact with Oxaliplatin?
MediHelp also lists interactions of Oxaliplatin with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal. The full list is on the Oxaliplatin page.
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