Drug interactions
Paromomycin + Torsemide
Severity: Moderate
Paromomycin and Torsemide: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Paromomycin is an aminoglycoside with minimal oral absorption, which can increase with intestinal ulceration or renal impairment. In that case combined use with a loop diuretic may add ototoxic and nephrotoxic risk.
What this interaction means in plain words
Paromomycin and Torsemide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Paromomycin belongs to Anti Bacterial; Torsemide belongs to Cardiovascular.
Why it happens
Potential additive ototoxicity and nephrotoxicity if systemic aminoglycoside absorption occurs.
What to do
Monitor renal function and hearing in patients with renal impairment or GI mucosal damage.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Torsemide
Other interactions of Paromomycin
- Cidofovir + Paromomycin Major
- Adefovir + Paromomycin Moderate
- Amikacin + Paromomycin Moderate
- Amphotericin b + Paromomycin Moderate
- Atracurium + Paromomycin Moderate
- Bacitracin-neomycin-polymyxin + Paromomycin Moderate
Frequently asked questions
Can I take Paromomycin with Torsemide?
MediHelp rates the interaction as moderate. Paromomycin and Torsemide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Paromomycin is an aminoglycoside with minimal oral absorption, which can increase with intestinal ulceration or renal impairment. In that case combined use with a loop diuretic may add ototoxic and nephrotoxic risk.
How serious is the interaction between Paromomycin and Torsemide?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor renal function and hearing in patients with renal impairment or GI mucosal damage.
What other medicines interact with Torsemide?
MediHelp also lists interactions of Torsemide with, for example, Amikacin, Amiodarone, Carbenoxolone. The full list is on the Torsemide page.
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