Drug interactions
Prednisone + Ubrogepant
Severity: Minor
Prednisone and Ubrogepant: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Prednisone is a weak CYP3A4 inducer at most, and any reduction in ubrogepant exposure would be small. A meaningful loss of effect is unlikely.
What this interaction means in plain words
Prednisone and Ubrogepant have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Prednisone belongs to Endocrine; Ubrogepant belongs to Central Nervous System.
Why it happens
Possible weak CYP3A4 induction by prednisone could slightly increase ubrogepant metabolism.
What to do
No dose adjustment is usually needed. Assess migraine response and consider the second dose per label if the response is inadequate.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Prednisone
- Bcg vaccine live + Prednisone Contraindicated
- Measles vaccine + Prednisone Contraindicated
- Mifepristone + Prednisone Contraindicated
- Prednisone + Radium-223 dichloride Contraindicated
- Prednisone + Smallpox vaccine live Contraindicated
- Adenovirus types 4 and 7 live + Prednisone Major
Other interactions of Ubrogepant
- Clarithromycin + Ubrogepant Contraindicated
- Itraconazole + Ubrogepant Contraindicated
- Ketoconazole + Ubrogepant Contraindicated
- Posaconazole + Ubrogepant Contraindicated
- Ubrogepant + Voriconazole Contraindicated
- Apalutamide + Ubrogepant Major
Frequently asked questions
Can I take Prednisone with Ubrogepant?
MediHelp rates the interaction as minor. Prednisone and Ubrogepant have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Prednisone is a weak CYP3A4 inducer at most, and any reduction in ubrogepant exposure would be small. A meaningful loss of effect is unlikely.
How serious is the interaction between Prednisone and Ubrogepant?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose adjustment is usually needed. Assess migraine response and consider the second dose per label if the response is inadequate.
What other medicines interact with Prednisone?
MediHelp also lists interactions of Prednisone with, for example, Bcg vaccine live, Measles vaccine, Mifepristone. The full list is on the Prednisone page.
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