Drug interactions
Rimegepant + Rucaparib
Severity: Minor
Rimegepant and Rucaparib: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Rucaparib is a weak inhibitor of CYP3A4 and may modestly increase rimegepant exposure. Clinical impact is expected to be small.
What this interaction means in plain words
Rimegepant and Rucaparib have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Rimegepant belongs to Central Nervous System; Rucaparib belongs to Oncology.
Why it happens
Weak inhibition of CYP3A4 metabolism of rimegepant by rucaparib.
What to do
No routine dose change is needed; monitor for rimegepant adverse effects such as nausea.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Rimegepant
Other interactions of Rucaparib
- Cisapride + Rucaparib Major
- Ergotamine + Rucaparib Major
- Pimozide + Rucaparib Major
- Alfuzosin + Rucaparib Moderate
- Aripiprazole + Rucaparib Moderate
- Atorvastatin + Rucaparib Moderate
Frequently asked questions
Can I take Rimegepant with Rucaparib?
MediHelp rates the interaction as minor. Rimegepant and Rucaparib have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Rucaparib is a weak inhibitor of CYP3A4 and may modestly increase rimegepant exposure. Clinical impact is expected to be small.
How serious is the interaction between Rimegepant and Rucaparib?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine dose change is needed; monitor for rimegepant adverse effects such as nausea.
What other medicines interact with Rimegepant?
MediHelp also lists interactions of Rimegepant with, for example, Amobarbital, Atazanavir, Butabarbital. The full list is on the Rimegepant page.
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