Drug interactions
Salmeterol + Solriamfetol
Severity: Moderate
Salmeterol and Solriamfetol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Solriamfetol, a dopamine and norepinephrine reuptake inhibitor, can raise blood pressure and heart rate, and with salmeterol these effects may be additive. The risk is greater in patients with cardiovascular disease.
What this interaction means in plain words
Salmeterol and Solriamfetol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Salmeterol belongs to Respiratory; Solriamfetol belongs to Central Nervous System.
Why it happens
Additive sympathomimetic cardiovascular effects.
What to do
Monitor blood pressure and heart rate and adjust therapy if hypertension or tachycardia develops.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Salmeterol
- Ritonavir + Salmeterol Contraindicated
- Salmeterol + Saquinavir Contraindicated
- Amitriptyline + Salmeterol Major
- Arformoterol + Salmeterol Major
- Atazanavir + Salmeterol Major
- Budesonide-formoterol + Salmeterol Major
Other interactions of Solriamfetol
- Isocarboxazid + Solriamfetol Contraindicated
- Linezolid + Solriamfetol Contraindicated
- Phenelzine + Solriamfetol Contraindicated
- Procarbazine + Solriamfetol Contraindicated
- Rasagiline + Solriamfetol Contraindicated
- Safinamide + Solriamfetol Contraindicated
Frequently asked questions
Can I take Salmeterol with Solriamfetol?
MediHelp rates the interaction as moderate. Salmeterol and Solriamfetol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Solriamfetol, a dopamine and norepinephrine reuptake inhibitor, can raise blood pressure and heart rate, and with salmeterol these effects may be additive. The risk is greater in patients with cardiovascular disease.
How serious is the interaction between Salmeterol and Solriamfetol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and heart rate and adjust therapy if hypertension or tachycardia develops.
What other medicines interact with Salmeterol?
MediHelp also lists interactions of Salmeterol with, for example, Ritonavir, Saquinavir, Amitriptyline. The full list is on the Salmeterol page.
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