Drug interactions
Saxagliptin-metformin + Vilazodone
Severity: Minor
Saxagliptin-metformin and Vilazodone: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Serotonergic antidepressants can occasionally alter glucose levels and lead to hypoglycemia in patients taking antidiabetic drugs. The effect is generally mild and unpredictable.
What this interaction means in plain words
Saxagliptin-metformin and Vilazodone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Saxagliptin-metformin belongs to Endocrine; Vilazodone belongs to Central Nervous System.
Why it happens
Possible additive glucose lowering through serotonergic effects on insulin sensitivity; not well established.
What to do
Monitor glucose when starting or stopping vilazodone. Reduce antidiabetic doses if hypoglycemia occurs.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Saxagliptin-metformin
Other interactions of Vilazodone
- Isocarboxazid + Vilazodone Contraindicated
- Methylene blue + Vilazodone Contraindicated
- Phenelzine + Vilazodone Contraindicated
- Rasagiline + Vilazodone Contraindicated
- Selegiline transdermal + Vilazodone Contraindicated
- Selegiline + Vilazodone Contraindicated
Frequently asked questions
Can I take Saxagliptin-metformin with Vilazodone?
MediHelp rates the interaction as minor. Saxagliptin-metformin and Vilazodone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Serotonergic antidepressants can occasionally alter glucose levels and lead to hypoglycemia in patients taking antidiabetic drugs. The effect is generally mild and unpredictable.
How serious is the interaction between Saxagliptin-metformin and Vilazodone?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor glucose when starting or stopping vilazodone. Reduce antidiabetic doses if hypoglycemia occurs.
What other medicines interact with Saxagliptin-metformin?
MediHelp also lists interactions of Saxagliptin-metformin with, for example, Atazanavir, Clozapine, Contrast media. The full list is on the Saxagliptin-metformin page.
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