Drug interactions
Solifenacin + Triclabendazole
Severity: Moderate
Solifenacin and Triclabendazole: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Triclabendazole may prolong the QT interval, and solifenacin has dose-related QT effects, so the combination may add to arrhythmia risk. The risk is greater with electrolyte disturbance or cardiac disease.
What this interaction means in plain words
Solifenacin and Triclabendazole can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Solifenacin belongs to Genitourinary; Triclabendazole belongs to Anti Parasitic.
Why it happens
Additive QT interval prolongation.
What to do
Check ECG and electrolytes if the patient has other QT risk factors. Consider holding solifenacin during the short triclabendazole course.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Solifenacin
Other interactions of Triclabendazole
Frequently asked questions
Can I take Solifenacin with Triclabendazole?
MediHelp rates the interaction as moderate. Solifenacin and Triclabendazole can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Triclabendazole may prolong the QT interval, and solifenacin has dose-related QT effects, so the combination may add to arrhythmia risk. The risk is greater with electrolyte disturbance or cardiac disease.
How serious is the interaction between Solifenacin and Triclabendazole?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check ECG and electrolytes if the patient has other QT risk factors. Consider holding solifenacin during the short triclabendazole course.
What other medicines interact with Solifenacin?
MediHelp also lists interactions of Solifenacin with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Solifenacin page.
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