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Drug interactions

Sucralfate + Tiratricol

Severity: Moderate

Sucralfate and Tiratricol: moderate interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Sucralfate binds to thyroid hormone analogues in the gut and may substantially reduce their absorption. This can lead to inadequate thyroid hormone effect.

What this interaction means in plain words

Sucralfate and Tiratricol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Sucralfate belongs to Gastrointestinal Tract; Tiratricol belongs to Endocrine.

Evidence level: Moderate

Why it happens

Sucralfate adsorbs or binds tiratricol in the gastrointestinal tract, impairing absorption.

What to do

Give tiratricol at least 2 hours before or apart from sucralfate, and monitor thyroid function.

What to ask your pharmacist

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Sucralfate with Tiratricol?

MediHelp rates the interaction as moderate. Sucralfate and Tiratricol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Sucralfate binds to thyroid hormone analogues in the gut and may substantially reduce their absorption. This can lead to inadequate thyroid hormone effect.

How serious is the interaction between Sucralfate and Tiratricol?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give tiratricol at least 2 hours before or apart from sucralfate, and monitor thyroid function.

What other medicines interact with Tiratricol?

MediHelp also lists interactions of Tiratricol with, for example, Levothyroxine, Calcium, Carbamazepine. The full list is on the Tiratricol page.

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