Drug interactions
Verapamil + Verteporfin
Severity: Minor
Verapamil and Verteporfin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Calcium channel blockers may increase cellular uptake of verteporfin and its photodynamic effect in vascular endothelium. The clinical consequence is uncertain.
What this interaction means in plain words
Verapamil and Verteporfin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Verapamil belongs to Cardiovascular; Verteporfin belongs to Miscellaneous.
Why it happens
Possible increased cellular uptake of verteporfin through effects on cell membrane and calcium handling; not firmly established.
What to do
No dose change is required; monitor treatment response and for photosensitivity-related effects.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Verapamil
- Dofetilide + Verapamil Contraindicated
- Flibanserin + Verapamil Contraindicated
- Lomitapide + Verapamil Contraindicated
- Lonafarnib + Verapamil Contraindicated
- Pimozide + Verapamil Contraindicated
- Acebutolol + Verapamil Major
Other interactions of Verteporfin
- Doxycycline + Verteporfin Moderate
- Griseofulvin + Verteporfin Moderate
- Minocycline + Verteporfin Moderate
- Tetracycline + Verteporfin Moderate
- Adapalene + Verteporfin Minor
- Amlodipine-hydrochlorothiazide-valsartan + Verteporfin Minor
Frequently asked questions
Can I take Verapamil with Verteporfin?
MediHelp rates the interaction as minor. Verapamil and Verteporfin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Calcium channel blockers may increase cellular uptake of verteporfin and its photodynamic effect in vascular endothelium. The clinical consequence is uncertain.
How serious is the interaction between Verapamil and Verteporfin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose change is required; monitor treatment response and for photosensitivity-related effects.
What other medicines interact with Verapamil?
MediHelp also lists interactions of Verapamil with, for example, Dofetilide, Flibanserin, Lomitapide. The full list is on the Verapamil page.
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