Interazioni tra farmaci
Aztreonam + Cefpirome
Gravità: Minore
Aztreonam and Cefpirome: minor interaction.
Ultimo aggiornamento
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Sintesi
Aztreonam and cefpirome are both beta-lactam antibiotics with activity against gram-negative bacteria, and the combination can show additive or synergistic killing of some Enterobacteriaceae in vitro. This is generally a therapeutic benefit rather than a harmful interaction, though both drugs can cause hypersensitivity reactions and cross-reactivity is possible with cephalosporins with similar side chains.
Cosa significa questa interazione in parole semplici
Aztreonam and Cefpirome have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Aztreonam belongs to Anti Bacterial; Cefpirome belongs to Anti Bacterial.
Perché avviene
Additive pharmacodynamic effect through binding of different penicillin-binding proteins in gram-negative bacteria.
Cosa fare
No routine adjustment is needed; use only when the combined spectrum is clinically intended and guided by culture results. Monitor for hypersensitivity reactions.
Cosa chiedere al farmacista
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Altre interazioni di Aztreonam
- Aztreonam + Cefoxitin Moderata
- Aztreonam + Cholera vaccine Moderata
- Aztreonam + Microbiota Moderata
- Aztreonam + Sodium picosulfate / magnesium oxide / anhydrous citric acid Moderata
- Aztreonam + Typhoid vaccine live Moderata
- Amikacin + Aztreonam Minore
Altre interazioni di Cefpirome
- Amikacin + Cefpirome Moderata
- Bupropion-naltrexone + Cefpirome Moderata
- Bupropion + Cefpirome Moderata
- Cefpirome + Dexamethasone-tobramycin Moderata
- Cefpirome + Gentamicin Moderata
- Cefpirome + Streptomycin Moderata
Domande frequenti
Can I take Aztreonam with Cefpirome?
MediHelp rates the interaction as minor. Aztreonam and Cefpirome have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Aztreonam and cefpirome are both beta-lactam antibiotics with activity against gram-negative bacteria, and the combination can show additive or synergistic killing of some Enterobacteriaceae in vitro. This is generally a therapeutic benefit rather than a harmful interaction, though both drugs can cause hypersensitivity reactions and cross-reactivity is possible with cephalosporins with similar side chains.
How serious is the interaction between Aztreonam and Cefpirome?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine adjustment is needed; use only when the combined spectrum is clinically intended and guided by culture results. Monitor for hypersensitivity reactions.
What other medicines interact with Aztreonam?
MediHelp also lists interactions of Aztreonam with, for example, Cefoxitin, Cholera vaccine, Microbiota. The full list is on the Aztreonam page.
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