相互作用
Colchicine + Fluvastatin
重症度: 中等度
Colchicine and Fluvastatin: moderate interaction.
最終更新日
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概要
Both drugs can cause myopathy, and the combination has been linked to rhabdomyolysis. Risk is greater in older patients and those with renal impairment.
この相互作用をわかりやすく説明すると
Colchicine and Fluvastatin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Colchicine belongs to Genitourinary; Fluvastatin belongs to Cardiovascular.
なぜ起こるのか
Additive myotoxicity.
対処法
Monitor for muscle pain, weakness and dark urine, and check creatine kinase if symptoms occur. Consider temporary statin interruption during colchicine courses in high-risk patients.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、ColchicineとFluvastatinの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Colchicineのその他の相互作用
Fluvastatinのその他の相互作用
よくある質問
Can I take Colchicine with Fluvastatin?
MediHelp rates the interaction as moderate. Colchicine and Fluvastatin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both drugs can cause myopathy, and the combination has been linked to rhabdomyolysis. Risk is greater in older patients and those with renal impairment.
How serious is the interaction between Colchicine and Fluvastatin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for muscle pain, weakness and dark urine, and check creatine kinase if symptoms occur. Consider temporary statin interruption during colchicine courses in high-risk patients.
What other medicines interact with Colchicine?
MediHelp also lists interactions of Colchicine with, for example, Clarithromycin, Cobicistat, Cyclosporine. The full list is on the Colchicine page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
