相互作用
Dronedarone + Haloperidol
重症度: 併用禁忌
Dronedarone and Haloperidol: contraindicated interaction.
最終更新日
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概要
Both agents can prolong QT, and haloperidol has well-documented torsades de pointes reports, particularly at higher doses or intravenously. Dronedarone labeling contraindicates use with drugs that prolong QT and may cause torsades de pointes.
この相互作用をわかりやすく説明すると
Dronedarone and Haloperidol are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Dronedarone belongs to Cardiovascular; Haloperidol belongs to Central Nervous System.
なぜ起こるのか
Additive pharmacodynamic QT prolongation.
対処法
Do not co-administer; choose an antipsychotic with lower QT liability or another antiarrhythmic strategy.
薬剤師に尋ねること
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Pro+会員向け
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アカウントを作成してPro+トライアルを始めると、DronedaroneとHaloperidolの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Dronedaroneのその他の相互作用
Haloperidolのその他の相互作用
よくある質問
Can I take Dronedarone with Haloperidol?
MediHelp rates the interaction as contraindicated. Dronedarone and Haloperidol are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Both agents can prolong QT, and haloperidol has well-documented torsades de pointes reports, particularly at higher doses or intravenously. Dronedarone labeling contraindicates use with drugs that prolong QT and may cause torsades de pointes.
How serious is the interaction between Dronedarone and Haloperidol?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not co-administer; choose an antipsychotic with lower QT liability or another antiarrhythmic strategy.
What other medicines interact with Dronedarone?
MediHelp also lists interactions of Dronedarone with, for example, Adagrasib, Amiodarone, Arsenic trioxide. The full list is on the Dronedarone page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
