相互作用
Fluvastatin + Oteseconazole
重症度: 中等度
Fluvastatin and Oteseconazole: moderate interaction.
最終更新日
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概要
Oteseconazole inhibits BCRP and can raise levels of BCRP substrates such as fluvastatin. Increased statin exposure raises the risk of muscle toxicity.
この相互作用をわかりやすく説明すると
Fluvastatin and Oteseconazole can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Fluvastatin belongs to Cardiovascular; Oteseconazole belongs to Anti Fungals.
なぜ起こるのか
Oteseconazole inhibits BCRP, increasing fluvastatin absorption and reducing efflux.
対処法
Start with the lowest fluvastatin dose or reduce the dose, and monitor for myopathy symptoms.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、FluvastatinとOteseconazoleの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Fluvastatinのその他の相互作用
Oteseconazoleのその他の相互作用
よくある質問
Can I take Fluvastatin with Oteseconazole?
MediHelp rates the interaction as moderate. Fluvastatin and Oteseconazole can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Oteseconazole inhibits BCRP and can raise levels of BCRP substrates such as fluvastatin. Increased statin exposure raises the risk of muscle toxicity.
How serious is the interaction between Fluvastatin and Oteseconazole?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Start with the lowest fluvastatin dose or reduce the dose, and monitor for myopathy symptoms.
What other medicines interact with Fluvastatin?
MediHelp also lists interactions of Fluvastatin with, for example, Cyclosporine, Cyclosporin, Gemfibrozil. The full list is on the Fluvastatin page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
