相互作用
Glycopyrrolate + Umeclidinium
重症度: 中等度
Glycopyrrolate and Umeclidinium: moderate interaction.
最終更新日
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概要
Systemic glycopyrrolate adds antimuscarinic effects to those of inhaled umeclidinium. This may increase dry mouth, constipation, urinary retention, tachycardia and intraocular pressure.
この相互作用をわかりやすく説明すると
Glycopyrrolate and Umeclidinium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Glycopyrrolate belongs to Respiratory; Umeclidinium belongs to Respiratory.
なぜ起こるのか
Additive muscarinic receptor antagonism.
対処法
Avoid concurrent long-term use when possible. Monitor for urinary retention, constipation and visual symptoms.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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アカウントを作成してPro+トライアルを始めると、GlycopyrrolateとUmeclidiniumの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Umeclidiniumのその他の相互作用
Glycopyrrolateのその他の相互作用
よくある質問
Can I take Glycopyrrolate with Umeclidinium?
MediHelp rates the interaction as moderate. Glycopyrrolate and Umeclidinium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Systemic glycopyrrolate adds antimuscarinic effects to those of inhaled umeclidinium. This may increase dry mouth, constipation, urinary retention, tachycardia and intraocular pressure.
How serious is the interaction between Glycopyrrolate and Umeclidinium?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid concurrent long-term use when possible. Monitor for urinary retention, constipation and visual symptoms.
What other medicines interact with Umeclidinium?
MediHelp also lists interactions of Umeclidinium with, for example, Tiotropium, Aclidinium, Atropine iv /. The full list is on the Umeclidinium page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
