相互作用
Colestipol + Vitamin k1
重症度: 中等度
Colestipol and Vitamin k1: moderate interaction.
最終更新日
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概要
Colestipol is a bile acid sequestrant that impairs absorption of fat-soluble vitamins, including vitamin K. Prolonged use may lower vitamin K status and, in susceptible patients, contribute to prolonged clotting times or bleeding.
この相互作用をわかりやすく説明すると
Colestipol and Vitamin k1 can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Colestipol belongs to Cardiovascular; Vitamin k1 belongs to Cardiovascular.
なぜ起こるのか
Colestipol binds bile acids in the gut, reducing micelle formation and absorption of oral vitamin K.
対処法
Give oral vitamin K at least 4 hours before or after colestipol. Monitor INR or prothrombin time in patients on long-term colestipol or with other risk factors for deficiency.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、ColestipolとVitamin k1の臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Vitamin k1のその他の相互作用
Colestipolのその他の相互作用
よくある質問
Can I take Colestipol with Vitamin k1?
MediHelp rates the interaction as moderate. Colestipol and Vitamin k1 can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Colestipol is a bile acid sequestrant that impairs absorption of fat-soluble vitamins, including vitamin K. Prolonged use may lower vitamin K status and, in susceptible patients, contribute to prolonged clotting times or bleeding.
How serious is the interaction between Colestipol and Vitamin k1?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give oral vitamin K at least 4 hours before or after colestipol. Monitor INR or prothrombin time in patients on long-term colestipol or with other risk factors for deficiency.
What other medicines interact with Vitamin k1?
MediHelp also lists interactions of Vitamin k1 with, for example, Warfarin, Cholestyramine, Ketorolac intranasal. The full list is on the Vitamin k1 page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
