相互作用
Orlistat + Vitamin k1
重症度: 中等度
Orlistat and Vitamin k1: moderate interaction.
最終更新日
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概要
Orlistat decreases absorption of fat-soluble vitamins including vitamin K, and reduced vitamin K status may occur with prolonged use. This matters most for patients taking warfarin, in whom INR may rise.
この相互作用をわかりやすく説明すると
Orlistat and Vitamin k1 can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Orlistat belongs to Miscellaneous; Vitamin k1 belongs to Cardiovascular.
なぜ起こるのか
Inhibition of gastrointestinal lipase reduces absorption of fat-soluble vitamins.
対処法
Take vitamin K-containing supplements at least 2 hours apart from orlistat. Monitor INR in patients on vitamin K antagonists.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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ページ全体を見る
アカウントを作成してPro+トライアルを始めると、OrlistatとVitamin k1の臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Orlistatのその他の相互作用
Vitamin k1のその他の相互作用
よくある質問
Can I take Orlistat with Vitamin k1?
MediHelp rates the interaction as moderate. Orlistat and Vitamin k1 can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Orlistat decreases absorption of fat-soluble vitamins including vitamin K, and reduced vitamin K status may occur with prolonged use. This matters most for patients taking warfarin, in whom INR may rise.
How serious is the interaction between Orlistat and Vitamin k1?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Take vitamin K-containing supplements at least 2 hours apart from orlistat. Monitor INR in patients on vitamin K antagonists.
What other medicines interact with Orlistat?
MediHelp also lists interactions of Orlistat with, for example, Cyclosporine, Cyclosporin, Triheptanoin. The full list is on the Orlistat page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
