Interações medicamentosas
Cefpodoxime + Didanosine
Gravidade: Moderada
Cefpodoxime and Didanosine: moderate interaction.
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Resumo
Didanosine chewable tablets and oral solution contain buffering agents that raise gastric pH, and cefpodoxime absorption depends on an acidic environment. Co-administration can lower cefpodoxime exposure and may reduce its efficacy.
O que esta interação significa em palavras simples
Cefpodoxime and Didanosine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Cefpodoxime belongs to Anti Bacterial; Didanosine belongs to Anti Virals.
Por que acontece
Buffered didanosine formulations increase gastric pH, reducing dissolution and absorption of cefpodoxime proxetil.
O que fazer
Give cefpodoxime at least 2 hours before buffered didanosine formulations. Monitor clinical response to the antibiotic.
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Outras interações de Cefpodoxime
- Aluminum hydroxide + Cefpodoxime Moderada
- Amikacin + Cefpodoxime Moderada
- Calcium carbonate + Cefpodoxime Moderada
- Calcium + Cefpodoxime Moderada
- Cefpodoxime + Cholera vaccine Moderada
- Cefpodoxime + Cimetidine Moderada
Outras interações de Didanosine
- Didanosine + Elvitegravir / cobicistat / emtricitabine / tenofovir df Contraindicada
- Didanosine + Hydroxycarbamide Contraindicada
- Didanosine + Hydroxyurea Contraindicada
- Didanosine + Ribavirin Contraindicada
- Didanosine + Stavudine Contraindicada
- Allopurinol + Didanosine Grave
Perguntas frequentes
Can I take Cefpodoxime with Didanosine?
MediHelp rates the interaction as moderate. Cefpodoxime and Didanosine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Didanosine chewable tablets and oral solution contain buffering agents that raise gastric pH, and cefpodoxime absorption depends on an acidic environment. Co-administration can lower cefpodoxime exposure and may reduce its efficacy.
How serious is the interaction between Cefpodoxime and Didanosine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give cefpodoxime at least 2 hours before buffered didanosine formulations. Monitor clinical response to the antibiotic.
What other medicines interact with Cefpodoxime?
MediHelp also lists interactions of Cefpodoxime with, for example, Aluminum hydroxide, Amikacin, Calcium carbonate. The full list is on the Cefpodoxime page.
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