Interações medicamentosas
Deutetrabenazine + Isocarboxazid
Gravidade: Contraindicada
Deutetrabenazine and Isocarboxazid: contraindicated interaction.
Última atualização
Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.
O conteúdo clínico desta página está disponível apenas em inglês.
Resumo
Deutetrabenazine must not be used with MAOIs. Combination may cause marked blood pressure and heart rate changes, and monoamine depletion with MAO inhibition is unpredictable.
O que esta interação significa em palavras simples
Deutetrabenazine and Isocarboxazid are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Deutetrabenazine belongs to Central Nervous System; Isocarboxazid belongs to Central Nervous System.
Por que acontece
VMAT2 inhibition alters monoamine storage while MAO inhibition blocks their breakdown, causing unpredictable adrenergic effects.
O que fazer
Avoid concurrent use and wait at least 14 days after stopping an MAOI before starting deutetrabenazine. Consider other management of chorea or tardive dyskinesia.
O que perguntar ao farmacêutico
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Para assinantes do Pro+
Desbloqueie a página completa
Crie uma conta e comece um teste do Pro+ para desbloquear a orientação completa de conduta para Deutetrabenazine e Isocarboxazid, as notas adicionais, os detalhes da evidência e o verificador de interações para uma prescrição completa.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Experimente o Pro+ grátis por 14 dias na web. Sem cartão.
Outras interações de Isocarboxazid
- 5-HTP + Isocarboxazid Contraindicada
- Amitriptyline + Isocarboxazid Contraindicada
- Amobarbital + Isocarboxazid Contraindicada
- Amoxapine + Isocarboxazid Contraindicada
- Apraclonidine + Isocarboxazid Contraindicada
- Atomoxetine + Isocarboxazid Contraindicada
Outras interações de Deutetrabenazine
- Deutetrabenazine + Linezolid Contraindicada
- Deutetrabenazine + Phenelzine Contraindicada
- Deutetrabenazine + Rasagiline Contraindicada
- Deutetrabenazine + Safinamide Contraindicada
- Deutetrabenazine + Selegiline Contraindicada
- Deutetrabenazine + Tranylcypromine Contraindicada
Perguntas frequentes
Can I take Deutetrabenazine with Isocarboxazid?
MediHelp rates the interaction as contraindicated. Deutetrabenazine and Isocarboxazid are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Deutetrabenazine must not be used with MAOIs. Combination may cause marked blood pressure and heart rate changes, and monoamine depletion with MAO inhibition is unpredictable.
How serious is the interaction between Deutetrabenazine and Isocarboxazid?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid concurrent use and wait at least 14 days after stopping an MAOI before starting deutetrabenazine. Consider other management of chorea or tardive dyskinesia.
What other medicines interact with Isocarboxazid?
MediHelp also lists interactions of Isocarboxazid with, for example, 5-HTP, Amitriptyline, Amobarbital. The full list is on the Isocarboxazid page.
Monografias completas, posologia e verificador de interações no app MediHelp
Abra a referência completa, verifique interações entre vários medicamentos e use as ferramentas de posologia no app MediHelp.
