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Interações medicamentosas

Gemifloxacin + Magnesium hydroxide

Gravidade: Grave

Gemifloxacin and Magnesium hydroxide: major interaction.

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Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.

O conteúdo clínico desta página está disponível apenas em inglês.

Resumo

Magnesium-containing antacids chelate gemifloxacin and reduce its absorption, risking subtherapeutic antibiotic levels.

O que esta interação significa em palavras simples

Gemifloxacin and Magnesium hydroxide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.

Gemifloxacin belongs to Anti Bacterial; Magnesium hydroxide belongs to Gastrointestinal Tract.

Nível de evidência: High

Por que acontece

Chelation of gemifloxacin by magnesium cations in the gut reduces absorption.

O que fazer

Give gemifloxacin at least 2 hours before or 3 hours after magnesium hydroxide.

O que perguntar ao farmacêutico

  • Does the benefit of taking both outweigh the risk in my case?
  • Do I need any blood test, ECG or other check while on both?
  • What early warning signs should I watch for, and what should I do if they appear?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Perguntas frequentes

Can I take Gemifloxacin with Magnesium hydroxide?

MediHelp rates the interaction as major. Gemifloxacin and Magnesium hydroxide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Magnesium-containing antacids chelate gemifloxacin and reduce its absorption, risking subtherapeutic antibiotic levels.

How serious is the interaction between Gemifloxacin and Magnesium hydroxide?

MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give gemifloxacin at least 2 hours before or 3 hours after magnesium hydroxide.

What other medicines interact with Magnesium hydroxide?

MediHelp also lists interactions of Magnesium hydroxide with, for example, Ciprofloxacin, Dolutegravir, Levofloxacin. The full list is on the Magnesium hydroxide page.

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