Interações medicamentosas
Levofloxacin + Magnesium hydroxide
Gravidade: Grave
Levofloxacin and Magnesium hydroxide: major interaction.
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Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.
O conteúdo clínico desta página está disponível apenas em inglês.
Resumo
Magnesium hydroxide chelates levofloxacin in the gut and reduces its bioavailability. This may compromise antibacterial efficacy.
O que esta interação significa em palavras simples
Levofloxacin and Magnesium hydroxide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Levofloxacin belongs to Anti Bacterial; Magnesium hydroxide belongs to Gastrointestinal Tract.
Por que acontece
Chelation of levofloxacin by magnesium cations in the gastrointestinal tract reduces absorption.
O que fazer
Give oral levofloxacin at least 2 hours before or after magnesium hydroxide.
O que perguntar ao farmacêutico
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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Outras interações de Magnesium hydroxide
Outras interações de Levofloxacin
- Dronedarone + Levofloxacin Contraindicada
- Ibutilide + Levofloxacin Contraindicada
- Levofloxacin + Thioridazine Contraindicada
- Levofloxacin + Vandetanib Contraindicada
- Levofloxacin + Ziprasidone Contraindicada
- Adagrasib + Levofloxacin Grave
Perguntas frequentes
Can I take Levofloxacin with Magnesium hydroxide?
MediHelp rates the interaction as major. Levofloxacin and Magnesium hydroxide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Magnesium hydroxide chelates levofloxacin in the gut and reduces its bioavailability. This may compromise antibacterial efficacy.
How serious is the interaction between Levofloxacin and Magnesium hydroxide?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give oral levofloxacin at least 2 hours before or after magnesium hydroxide.
What other medicines interact with Magnesium hydroxide?
MediHelp also lists interactions of Magnesium hydroxide with, for example, Ciprofloxacin, Dolutegravir, Gemifloxacin. The full list is on the Magnesium hydroxide page.
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