Interações medicamentosas
Magnesium hydroxide + Ofloxacin
Gravidade: Grave
Magnesium hydroxide and Ofloxacin: major interaction.
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Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.
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Resumo
Magnesium hydroxide chelates ofloxacin in the gut and reduces its absorption, which may result in subtherapeutic levels.
O que esta interação significa em palavras simples
Magnesium hydroxide and Ofloxacin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Magnesium hydroxide belongs to Gastrointestinal Tract; Ofloxacin belongs to Anti Bacterial.
Por que acontece
Chelation of ofloxacin by magnesium cations in the gastrointestinal tract reduces absorption.
O que fazer
Give ofloxacin at least 2 hours before or after magnesium hydroxide.
O que perguntar ao farmacêutico
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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Outras interações de Magnesium hydroxide
Outras interações de Ofloxacin
- Ofloxacin + Thioridazine Contraindicada
- Adagrasib + Ofloxacin Grave
- Amiodarone + Ofloxacin Grave
- Amisulpride + Ofloxacin Grave
- Anagrelide + Ofloxacin Grave
- Arsenic trioxide + Ofloxacin Grave
Perguntas frequentes
Can I take Magnesium hydroxide with Ofloxacin?
MediHelp rates the interaction as major. Magnesium hydroxide and Ofloxacin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Magnesium hydroxide chelates ofloxacin in the gut and reduces its absorption, which may result in subtherapeutic levels.
How serious is the interaction between Magnesium hydroxide and Ofloxacin?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give ofloxacin at least 2 hours before or after magnesium hydroxide.
What other medicines interact with Magnesium hydroxide?
MediHelp also lists interactions of Magnesium hydroxide with, for example, Ciprofloxacin, Dolutegravir, Gemifloxacin. The full list is on the Magnesium hydroxide page.
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