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Interações medicamentosas

Magnesium hydroxide + Moxifloxacin

Gravidade: Grave

Magnesium hydroxide and Moxifloxacin: major interaction.

Última atualização Fontes: US FDA label

Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.

O conteúdo clínico desta página está disponível apenas em inglês.

Resumo

Magnesium cations bind moxifloxacin in the gut and reduce its absorption, potentially lowering antibiotic effectiveness.

O que esta interação significa em palavras simples

Magnesium hydroxide and Moxifloxacin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.

Magnesium hydroxide belongs to Gastrointestinal Tract; Moxifloxacin belongs to Anti Bacterial.

Nível de evidência: High

Por que acontece

Chelation of moxifloxacin by magnesium cations in the gastrointestinal tract reduces absorption.

O que fazer

Give moxifloxacin at least 4 hours before or 8 hours after magnesium hydroxide, per labeling.

O que perguntar ao farmacêutico

  • Does the benefit of taking both outweigh the risk in my case?
  • Do I need any blood test, ECG or other check while on both?
  • What early warning signs should I watch for, and what should I do if they appear?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Referências

Perguntas frequentes

Can I take Magnesium hydroxide with Moxifloxacin?

MediHelp rates the interaction as major. Magnesium hydroxide and Moxifloxacin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Magnesium cations bind moxifloxacin in the gut and reduce its absorption, potentially lowering antibiotic effectiveness.

How serious is the interaction between Magnesium hydroxide and Moxifloxacin?

MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give moxifloxacin at least 4 hours before or 8 hours after magnesium hydroxide, per labeling.

What other medicines interact with Magnesium hydroxide?

MediHelp also lists interactions of Magnesium hydroxide with, for example, Ciprofloxacin, Dolutegravir, Gemifloxacin. The full list is on the Magnesium hydroxide page.

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