藥物交互作用
Apalutamide + Atogepant
嚴重程度: 中度
Apalutamide and Atogepant: moderate interaction.
最後更新
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摘要
Apalutamide is a strong CYP3A4 inducer and reduces atogepant exposure, which may weaken migraine prevention.
用白話說明這項交互作用的意義
Apalutamide and Atogepant can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Apalutamide belongs to Endocrine; Atogepant belongs to Central Nervous System.
為什麼會發生
Apalutamide induces CYP3A4, increasing atogepant metabolism.
處置方式
Use atogepant 30 mg or 60 mg once daily as labeled for strong CYP3A4 inducers. Monitor migraine frequency.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Apalutamide 的其他交互作用
Atogepant 的其他交互作用
常見問題
Can I take Apalutamide with Atogepant?
MediHelp rates the interaction as moderate. Apalutamide and Atogepant can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Apalutamide is a strong CYP3A4 inducer and reduces atogepant exposure, which may weaken migraine prevention.
How serious is the interaction between Apalutamide and Atogepant?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use atogepant 30 mg or 60 mg once daily as labeled for strong CYP3A4 inducers. Monitor migraine frequency.
What other medicines interact with Apalutamide?
MediHelp also lists interactions of Apalutamide with, for example, Cabotegravir, Cobicistat, Doravirine. The full list is on the Apalutamide page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
