藥品參考
Chlordiazepoxide-clidinium
Chlordiazepoxide-clidinium is a medicine in the class gastrointestinal tract. It is used for irritable bowel syndrome.
- 藥物類別: Gastrointestinal Tract
- 用途: irritable bowel syndrome
最後更新
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
重點資訊
- 藥物類別
- Gastrointestinal Tract
- 常見劑型
- 錠劑, 膠囊
- 常見規格
- 5 mg
- 已知交互作用
- 231 (嚴重: 65 · 中度: 134 · 輕微: 32)
- 商品名
- 11
- 國家與市場
- 3
用途
作用方式
Chlordiazepoxide: Benzodiazepine; depresses all levels of CNS, including limbic and reticular formation, possibly by increasing gamma-aminobutyric acid (GABA) activity, a major inhibitory neurotransmitter. Clidinium: Anticholinergic agent; elicits antispasmodic and antisecretory effects on GI tract.
成人常用劑量（仿單摘要）
Peptic Ulcer, IBS, & Enterocolitis: 1-2 cap PO q6-8hr AC and HS
懷孕與哺乳
- 懷孕
- Unsafe Chlordiazepoxide: late-pregnancy use can cause neonatal sedation, floppiness and withdrawal; no clear birth-defect risk. Clidinium (anticholinergic): no adequate data. Avoid, especially near term; use only if clearly needed.
- 哺乳
- Unknown Chlordiazepoxide: no milk data; it and its long-acting metabolites could sedate the infant (LactMed: prefer an alternative). Clidinium, an anticholinergic, may reduce milk supply. Prefer alternatives; if used, watch the infant for sedation and poor feeding and watch milk supply.
已通報的副作用
- Drowsiness
- Ataxia
- Xerostomia
禁忌症
- Hypersensitivity
- Glaucoma
- Prostatic hypertrophy
哪些人需要特別留意
- Contraindicated in Glaucoma, Prostatic hypertrophy, Severe respiratory depression.
- Concomitant use of benzodiazepines and opioids may result in profound respiratory depression, coma, and death.
請告知藥師或醫師您是否懷孕或哺乳、是否患有腎臟或肝臟疾病、是否有過敏，以及您正在使用的所有其他藥物或保健品。
重要交互作用 (231)
- Alfentanil + Chlordiazepoxide-clidinium Major
- Alprazolam + Chlordiazepoxide-clidinium Major
- Amobarbital + Chlordiazepoxide-clidinium Major
- Belladonna and opium + Chlordiazepoxide-clidinium Major
- Benzhydrocodone / acetaminophen + Chlordiazepoxide-clidinium Major
- Brexanolone + Chlordiazepoxide-clidinium Major
- Buprenorphine + Chlordiazepoxide-clidinium Major
- Buprenorphine buccal + Chlordiazepoxide-clidinium Major
- Buprenorphine long-acting + Chlordiazepoxide-clidinium Major
- Buprenorphine subdermal implant + Chlordiazepoxide-clidinium Major
Pro+ 會員專屬
解鎖完整頁面
建立帳號並開始 Pro+ 試用，即可開啟 Chlordiazepoxide-clidinium 的完整藥品專論：劑量、懷孕與哺乳、副作用、警示及所有交互作用。
- Dosing by age, kidney and liver function, and further dose lines
- Renal and hepatic dose adjustments
- Paediatric dosing
- Dosing in older adults
- Pharmacokinetics
- Patient counselling points
- Food interactions
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同類別的其他藥品
常見問題
What is Chlordiazepoxide-clidinium used for?
Chlordiazepoxide-clidinium is a medicine in the class gastrointestinal tract. It is used for Irritable bowel syndrome, Peptic ulcer.
What side effects have been reported with Chlordiazepoxide-clidinium?
Drowsiness, Ataxia, Xerostomia.
Can Chlordiazepoxide-clidinium be taken in pregnancy or while breastfeeding?
Pregnancy: Unsafe. Chlordiazepoxide: late-pregnancy use can cause neonatal sedation, floppiness and withdrawal; no clear birth-defect risk. Clidinium (anticholinergic): no adequate data. Avoid, especially near term; use only if clearly needed. Breastfeeding: Unknown. Chlordiazepoxide: no milk data; it and its long-acting metabolites could sedate the infant (LactMed: prefer an alternative). Clidinium, an anticholinergic, may reduce milk supply. Prefer alternatives; if used, watch the infant for sedation and poor feeding and watch milk supply.
What does Chlordiazepoxide-clidinium interact with?
MediHelp lists 231 known interactions for Chlordiazepoxide-clidinium. Major: 65 · Moderate: 134 · Minor: 32. The most serious include Alfentanil, Alprazolam, Amobarbital.
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