藥品參考
Pefloxacin
Pefloxacin is a medicine in the class anti bacterial. It is used for bacterial infections.
- 藥物類別: Anti Bacterial
- 用途: bacterial infections
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本頁的臨床內容僅提供英文版。
重點資訊
- 藥物類別
- Anti Bacterial
- 常見劑型
- 錠劑
- 常見規格
- 400 mg
- 已知交互作用
- 15 (禁忌併用: 1 · 嚴重: 3 · 中度: 10 · 輕微: 1)
- 商品名
- 5
- 國家與市場
- 2
用途
作用方式
Pefloxacin exerts its bactericidal action via the inhibition of the essential bacterial enzyme DNA gyrase (DNA Topoisomerase II).
成人常用劑量（仿單摘要）
400 mg bid 7 to 10 days taken along with food.
懷孕與哺乳
- 懷孕
- Unsafe Fluoroquinolone. EU national labels (e.g. Romania) contraindicate it in pregnancy because of possible cartilage damage, seen in young animals; human data for the class show no clear rise in birth defects. Avoid unless no safer alternative; inadvertent use is not a reason to end a pregnancy.
- 哺乳
- Unknown No human milk data; no LactMed or e-lactancia record. EU national labels (e.g. Romania) contraindicate it while breastfeeding (possible cartilage damage). LactMed accepts ciprofloxacin or levofloxacin with infant monitoring; prefer one of them or a non-quinolone.
已通報的副作用
- Headache
- Vomiting
- Nausea
- Dizziness
- Difficulty in falling or staying asleep
哪些人需要特別留意
- In prolonged therapy, perform periodic evaluations of organ system function (eg, renal, hepatic, hematopoietic)
- Not drug of first choice in pediatrics due to increased incidence of adverse events compared to controls, including arthropathy
請告知藥師或醫師您是否懷孕或哺乳、是否患有腎臟或肝臟疾病、是否有過敏，以及您正在使用的所有其他藥物或保健品。
重要交互作用 (15)
- Pefloxacin + Tizanidine Contraindicated
- Clozapine + Pefloxacin Major
- Duloxetine + Pefloxacin Major
- Pefloxacin + Theophylline Major
- Asenapine + Pefloxacin Moderate
- Caffeine + Pefloxacin Moderate
- Cimetidine + Pefloxacin Moderate
- Clomipramine + Pefloxacin Moderate
- Imipramine + Pefloxacin Moderate
- Lidocaine + Pefloxacin Moderate
同類別的其他藥品
常見問題
What is Pefloxacin used for?
Pefloxacin is a medicine in the class anti bacterial. It is used for Bacterial infections.
What side effects have been reported with Pefloxacin?
Headache, Vomiting, Nausea, Dizziness, Difficulty in falling or staying asleep.
Can Pefloxacin be taken in pregnancy or while breastfeeding?
Pregnancy: Unsafe. Fluoroquinolone. EU national labels (e.g. Romania) contraindicate it in pregnancy because of possible cartilage damage, seen in young animals; human data for the class show no clear rise in birth defects. Avoid unless no safer alternative; inadvertent use is not a reason to end a pregnancy. Breastfeeding: Unknown. No human milk data; no LactMed or e-lactancia record. EU national labels (e.g. Romania) contraindicate it while breastfeeding (possible cartilage damage). LactMed accepts ciprofloxacin or levofloxacin with infant monitoring; prefer one of them or a non-quinolone.
What does Pefloxacin interact with?
MediHelp lists 15 known interactions for Pefloxacin. Contraindicated: 1 · Major: 3 · Moderate: 10 · Minor: 1. The most serious include Tizanidine, Clozapine, Duloxetine.
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