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藥物交互作用

Amikacin + Cefpirome

嚴重程度: 中度

Amikacin and Cefpirome: moderate interaction.

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僅供醫療專業人員參考。本頁為簡要摘要,並非醫療建議,亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。

本頁的臨床內容僅提供英文版。

摘要

Concurrent cephalosporins and aminoglycosides have been associated with greater kidney injury in some reports. The effect is generally modest but may matter in patients with existing renal impairment.

用白話說明這項交互作用的意義

Amikacin and Cefpirome can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Amikacin belongs to Anti Bacterial; Cefpirome belongs to Anti Bacterial.

證據等級: Low

為什麼會發生

Possible additive nephrotoxicity.

處置方式

Monitor serum creatinine and amikacin concentrations, keep patients well hydrated, and adjust the amikacin dose to renal function.

可向藥師詢問的問題

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

Pro+ 會員專屬

解鎖完整頁面

建立帳號並開始 Pro+ 試用,即可解鎖 Amikacin 與 Cefpirome 的完整臨床處置建議、補充說明、證據詳情及整張處方的交互作用檢查工具。

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

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常見問題

Can I take Amikacin with Cefpirome?

MediHelp rates the interaction as moderate. Amikacin and Cefpirome can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Concurrent cephalosporins and aminoglycosides have been associated with greater kidney injury in some reports. The effect is generally modest but may matter in patients with existing renal impairment.

How serious is the interaction between Amikacin and Cefpirome?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum creatinine and amikacin concentrations, keep patients well hydrated, and adjust the amikacin dose to renal function.

What other medicines interact with Amikacin?

MediHelp also lists interactions of Amikacin with, for example, Cidofovir, Adefovir, Amphotericin b. The full list is on the Amikacin page.

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