藥物交互作用
Cefpirome + Streptomycin
嚴重程度: 中度
Cefpirome and Streptomycin: moderate interaction.
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摘要
Cephalosporins given with aminoglycosides have been associated with increased kidney injury in some reports, though the effect is inconsistent and is modest for newer agents. Combination is common in practice.
用白話說明這項交互作用的意義
Cefpirome and Streptomycin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Cefpirome belongs to Anti Bacterial; Streptomycin belongs to Anti Bacterial.
為什麼會發生
Possible additive nephrotoxicity; mechanism is not well established.
處置方式
Monitor serum creatinine and urine output during combined therapy and adjust the streptomycin dose according to renal function.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Streptomycin 的其他交互作用
Cefpirome 的其他交互作用
常見問題
Can I take Cefpirome with Streptomycin?
MediHelp rates the interaction as moderate. Cefpirome and Streptomycin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Cephalosporins given with aminoglycosides have been associated with increased kidney injury in some reports, though the effect is inconsistent and is modest for newer agents. Combination is common in practice.
How serious is the interaction between Cefpirome and Streptomycin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum creatinine and urine output during combined therapy and adjust the streptomycin dose according to renal function.
What other medicines interact with Streptomycin?
MediHelp also lists interactions of Streptomycin with, for example, Abobotulinumtoxina, Adefovir, Amikacin. The full list is on the Streptomycin page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用,並使用劑量工具。