藥物交互作用
Cefpirome + Dexamethasone-tobramycin
嚴重程度: 中度
Cefpirome and Dexamethasone-tobramycin: moderate interaction.
最後更新
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摘要
Cefpirome with an aminoglycoside may add to kidney injury risk, as reported for cephalosporin-aminoglycoside combinations generally, particularly in patients with renal impairment.
用白話說明這項交互作用的意義
Cefpirome and Dexamethasone-tobramycin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Cefpirome belongs to Anti Bacterial; Dexamethasone-tobramycin belongs to Anti Bacterial.
為什麼會發生
Possible additive nephrotoxicity; mechanism not firmly established.
處置方式
Monitor serum creatinine and tobramycin concentrations, and adjust doses for renal function.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Dexamethasone-tobramycin 的其他交互作用
Cefpirome 的其他交互作用
常見問題
Can I take Cefpirome with Dexamethasone-tobramycin?
MediHelp rates the interaction as moderate. Cefpirome and Dexamethasone-tobramycin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Cefpirome with an aminoglycoside may add to kidney injury risk, as reported for cephalosporin-aminoglycoside combinations generally, particularly in patients with renal impairment.
How serious is the interaction between Cefpirome and Dexamethasone-tobramycin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum creatinine and tobramycin concentrations, and adjust doses for renal function.
What other medicines interact with Dexamethasone-tobramycin?
MediHelp also lists interactions of Dexamethasone-tobramycin with, for example, Capreomycin, Carboplatin, Ciprofloxacin. The full list is on the Dexamethasone-tobramycin page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
