藥品參考
Cefpirome
Cefpirome is a medicine in the class anti bacterial. It is used for febrile neutropenia.
- 藥物類別: Anti Bacterial
- 用途: febrile neutropenia
最後更新
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重點資訊
- 藥物類別
- Anti Bacterial
- 常見劑型
- 注射劑
- 常見規格
- 1 g, 2 g
- 已知交互作用
- 45 (中度: 6 · 輕微: 39)
- 商品名
- 2
- 國家與市場
- 1
用途
作用方式
Fourth-generation cephalosporin; has gram-negative coverage comparable to ceftazidime but better gram-positive coverage (comparable to ceftriaxone); is zwitterion and rapidly penetrates gram-negative cells; is best beta-lactam for IM administration; has poor capacity to cross blood-brain barrier and thus is not used for treatment of meningitis
成人常用劑量（仿單摘要）
1-4 g IV every 12 hours.
懷孕與哺乳
- 懷孕
- Unknown No human data; animal studies showed no harm. Product labels say safety in pregnancy is not established and it must not be used in pregnancy. Cephalosporins as a class have not shown birth-defect risk; prefer a better-studied cephalosporin.
- 哺乳
- Safe Passes into milk; labels advise stopping breastfeeding or the drug. No infant data. e-lactancia: likely compatible, as cephalosporins reach milk in insignificant amounts; prefer a better-studied cephalosporin, especially with a newborn or preterm infant.
已通報的副作用
- Rash
- Positive Coombs test result without hemolysis
- Elevated alanine aminotransferase
- Hypophosphatemia
哪些人需要特別留意
- If CrCl <60 mL/min, adjust dosage to compensate for slower renal elimination rate
- Caution warranted with history of previous immediate hypersensitivity reactions to cefpirome, cephalosporins, penicillins, or other drugs
- Prescribing drug in the absence of a proven or strongly suspected bacterial infection or a prophylactic indication is unlikely to provide benefit to patient
請告知藥師或醫師您是否懷孕或哺乳、是否患有腎臟或肝臟疾病、是否有過敏，以及您正在使用的所有其他藥物或保健品。
重要交互作用 (45)
- Amikacin + Cefpirome Moderate
- Bupropion + Cefpirome Moderate
- Bupropion-naltrexone + Cefpirome Moderate
- Cefpirome + Dexamethasone-tobramycin Moderate
- Cefpirome + Gentamicin Moderate
- Cefpirome + Streptomycin Moderate
- Acetylsalicylic acid + Cefpirome Minor
- Amlodipine-hydrochlorothiazide-valsartan + Cefpirome Minor
- Amlodipine-olmesartan-hydrochlorothiazide + Cefpirome Minor
- Atenolol-chlorthalidone + Cefpirome Minor
同類別的其他藥品
常見問題
What is Cefpirome used for?
Cefpirome is a medicine in the class anti bacterial. It is used for Febrile neutropenia, Intra-abdominal infections, Pneumonia, Skin infections, Urinary tract infections.
What side effects have been reported with Cefpirome?
Rash, Positive Coombs test result without hemolysis, Elevated alanine aminotransferase, Hypophosphatemia.
Can Cefpirome be taken in pregnancy or while breastfeeding?
Pregnancy: Unknown. No human data; animal studies showed no harm. Product labels say safety in pregnancy is not established and it must not be used in pregnancy. Cephalosporins as a class have not shown birth-defect risk; prefer a better-studied cephalosporin. Breastfeeding: Safe. Passes into milk; labels advise stopping breastfeeding or the drug. No infant data. e-lactancia: likely compatible, as cephalosporins reach milk in insignificant amounts; prefer a better-studied cephalosporin, especially with a newborn or preterm infant.
What does Cefpirome interact with?
MediHelp lists 45 known interactions for Cefpirome. Moderate: 6 · Minor: 39. The most serious include Amikacin, Bupropion, Bupropion-naltrexone.
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