藥物交互作用
Amiodarone + Panobinostat
嚴重程度: 禁忌併用
Amiodarone and Panobinostat: contraindicated interaction.
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摘要
Both drugs prolong the QT interval, and panobinostat labeling advises against using it with QT-prolonging agents. The combination increases the risk of torsades de pointes and sudden death.
用白話說明這項交互作用的意義
Amiodarone and Panobinostat are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Amiodarone belongs to Cardiovascular; Panobinostat belongs to Oncology.
為什麼會發生
Additive pharmacodynamic QT prolongation.
處置方式
Do not combine; select an alternative antiarrhythmic or anticancer approach. Amiodarone's long half-life means effects persist after stopping.
可向藥師詢問的問題
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Amiodarone 的其他交互作用
Panobinostat 的其他交互作用
常見問題
Can I take Amiodarone with Panobinostat?
MediHelp rates the interaction as contraindicated. Amiodarone and Panobinostat are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Both drugs prolong the QT interval, and panobinostat labeling advises against using it with QT-prolonging agents. The combination increases the risk of torsades de pointes and sudden death.
How serious is the interaction between Amiodarone and Panobinostat?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not combine; select an alternative antiarrhythmic or anticancer approach. Amiodarone's long half-life means effects persist after stopping.
What other medicines interact with Amiodarone?
MediHelp also lists interactions of Amiodarone with, for example, Amisulpride, Arsenic trioxide, Dofetilide. The full list is on the Amiodarone page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
