藥物交互作用
Amiodarone + Thalidomide
嚴重程度: 中度
Amiodarone and Thalidomide: moderate interaction.
最後更新
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本頁的臨床內容僅提供英文版。
摘要
Both thalidomide and long-term amiodarone can cause peripheral neuropathy. Concurrent use may raise the risk of sensory or motor nerve damage. Thalidomide can also cause bradycardia, which may add to amiodarone's effects on heart rate.
用白話說明這項交互作用的意義
Amiodarone and Thalidomide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Amiodarone belongs to Cardiovascular; Thalidomide belongs to Miscellaneous.
為什麼會發生
Additive neurotoxicity; additive bradycardic effects.
處置方式
Perform periodic neurological assessments and monitor heart rate and ECG. Modify therapy if neuropathy or symptomatic bradycardia develops.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Thalidomide 的其他交互作用
Amiodarone 的其他交互作用
常見問題
Can I take Amiodarone with Thalidomide?
MediHelp rates the interaction as moderate. Amiodarone and Thalidomide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both thalidomide and long-term amiodarone can cause peripheral neuropathy. Concurrent use may raise the risk of sensory or motor nerve damage. Thalidomide can also cause bradycardia, which may add to amiodarone's effects on heart rate.
How serious is the interaction between Amiodarone and Thalidomide?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Perform periodic neurological assessments and monitor heart rate and ECG. Modify therapy if neuropathy or symptomatic bradycardia develops.
What other medicines interact with Thalidomide?
MediHelp also lists interactions of Thalidomide with, for example, Bortezomib, Carbamazepine, Griseofulvin. The full list is on the Thalidomide page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
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