藥物交互作用
Amisulpride + Dexchlorpheniramine
嚴重程度: 中度
Amisulpride and Dexchlorpheniramine: moderate interaction.
最後更新
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摘要
A first-generation antihistamine combined with amisulpride may produce more sedation and psychomotor impairment than either drug alone. Older patients are at higher risk of confusion and falls.
用白話說明這項交互作用的意義
Amisulpride and Dexchlorpheniramine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Amisulpride belongs to Central Nervous System; Dexchlorpheniramine belongs to Respiratory.
為什麼會發生
Additive CNS depression from H1 antagonism and dopamine D2 antagonism.
處置方式
Use a non-sedating antihistamine as an alternative when feasible. Counsel on drowsiness and monitor older patients for confusion.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Amisulpride 的其他交互作用
Dexchlorpheniramine 的其他交互作用
常見問題
Can I take Amisulpride with Dexchlorpheniramine?
MediHelp rates the interaction as moderate. Amisulpride and Dexchlorpheniramine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. A first-generation antihistamine combined with amisulpride may produce more sedation and psychomotor impairment than either drug alone. Older patients are at higher risk of confusion and falls.
How serious is the interaction between Amisulpride and Dexchlorpheniramine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use a non-sedating antihistamine as an alternative when feasible. Counsel on drowsiness and monitor older patients for confusion.
What other medicines interact with Amisulpride?
MediHelp also lists interactions of Amisulpride with, for example, Amiodarone, Arsenic trioxide, Disopyramide. The full list is on the Amisulpride page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
