藥物交互作用
Azelastine + Dexchlorpheniramine
嚴重程度: 中度
Azelastine and Dexchlorpheniramine: moderate interaction.
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摘要
Both are H1 antihistamines, and dexchlorpheniramine is sedating and anticholinergic. Combined use duplicates therapy and increases drowsiness and anticholinergic effects.
用白話說明這項交互作用的意義
Azelastine and Dexchlorpheniramine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Azelastine belongs to Respiratory; Dexchlorpheniramine belongs to Respiratory.
為什麼會發生
Duplicate H1 antagonism producing additive sedation and anticholinergic effects.
處置方式
Avoid concurrent use and choose one antihistamine. If unavoidable, monitor for sedation and anticholinergic effects.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Azelastine 的其他交互作用
Dexchlorpheniramine 的其他交互作用
常見問題
Can I take Azelastine with Dexchlorpheniramine?
MediHelp rates the interaction as moderate. Azelastine and Dexchlorpheniramine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both are H1 antihistamines, and dexchlorpheniramine is sedating and anticholinergic. Combined use duplicates therapy and increases drowsiness and anticholinergic effects.
How serious is the interaction between Azelastine and Dexchlorpheniramine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid concurrent use and choose one antihistamine. If unavoidable, monitor for sedation and anticholinergic effects.
What other medicines interact with Azelastine?
MediHelp also lists interactions of Azelastine with, for example, Calcium / magnesium / potassium / sodium oxybates, Methadone, Sodium oxybate. The full list is on the Azelastine page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
