藥物交互作用
Amisulpride + Ondansetron
嚴重程度: 嚴重
Amisulpride and Ondansetron: major interaction.
最後更新
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摘要
Both drugs prolong the QT interval, and intravenous amisulpride for nausea carries a labeled warning about other QT-prolonging drugs. Together they raise the risk of torsades de pointes.
用白話說明這項交互作用的意義
Amisulpride and Ondansetron can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Amisulpride belongs to Central Nervous System; Ondansetron belongs to Gastrointestinal Tract.
為什麼會發生
Additive prolongation of cardiac repolarization.
處置方式
Avoid or use another antiemetic where feasible. If given together, correct electrolytes and monitor the ECG.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Ondansetron 的其他交互作用
Amisulpride 的其他交互作用
常見問題
Can I take Amisulpride with Ondansetron?
MediHelp rates the interaction as major. Amisulpride and Ondansetron can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Both drugs prolong the QT interval, and intravenous amisulpride for nausea carries a labeled warning about other QT-prolonging drugs. Together they raise the risk of torsades de pointes.
How serious is the interaction between Amisulpride and Ondansetron?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid or use another antiemetic where feasible. If given together, correct electrolytes and monitor the ECG.
What other medicines interact with Ondansetron?
MediHelp also lists interactions of Ondansetron with, for example, Apomorphine, Thioridazine, Vandetanib. The full list is on the Ondansetron page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
