藥物交互作用
Ondansetron + Vandetanib
嚴重程度: 禁忌併用
Ondansetron and Vandetanib: contraindicated interaction.
最後更新
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摘要
Vandetanib has a boxed warning for QT prolongation, torsades de pointes and sudden death. Ondansetron adds to the QT effect and the combination should be avoided.
用白話說明這項交互作用的意義
Ondansetron and Vandetanib are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Ondansetron belongs to Gastrointestinal Tract; Vandetanib belongs to Oncology.
為什麼會發生
Additive pharmacodynamic QT prolongation.
處置方式
Avoid the combination and use an antiemetic without QT effect. Vandetanib labeling advises against concomitant QT-prolonging drugs.
可向藥師詢問的問題
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Ondansetron 的其他交互作用
Vandetanib 的其他交互作用
常見問題
Can I take Ondansetron with Vandetanib?
MediHelp rates the interaction as contraindicated. Ondansetron and Vandetanib are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Vandetanib has a boxed warning for QT prolongation, torsades de pointes and sudden death. Ondansetron adds to the QT effect and the combination should be avoided.
How serious is the interaction between Ondansetron and Vandetanib?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination and use an antiemetic without QT effect. Vandetanib labeling advises against concomitant QT-prolonging drugs.
What other medicines interact with Ondansetron?
MediHelp also lists interactions of Ondansetron with, for example, Apomorphine, Thioridazine, Adagrasib. The full list is on the Ondansetron page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
