藥物交互作用
Amlodipine-olmesartan + Colesevelam
嚴重程度: 中度
Amlodipine-olmesartan and Colesevelam: moderate interaction.
最後更新
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
摘要
Colesevelam binds olmesartan in the gut and reduces its absorption, which may weaken blood pressure control. The effect is greatest when both are taken at the same time.
用白話說明這項交互作用的意義
Amlodipine-olmesartan and Colesevelam can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Amlodipine-olmesartan belongs to Cardiovascular; Colesevelam belongs to Endocrine.
為什麼會發生
Bile acid sequestrant binding of olmesartan in the gastrointestinal tract reduces its absorption.
處置方式
Give olmesartan at least 4 hours before colesevelam. Monitor blood pressure if dosing times cannot be separated.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Amlodipine-olmesartan 的其他交互作用
Colesevelam 的其他交互作用
常見問題
Can I take Amlodipine-olmesartan with Colesevelam?
MediHelp rates the interaction as moderate. Amlodipine-olmesartan and Colesevelam can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Colesevelam binds olmesartan in the gut and reduces its absorption, which may weaken blood pressure control. The effect is greatest when both are taken at the same time.
How serious is the interaction between Amlodipine-olmesartan and Colesevelam?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give olmesartan at least 4 hours before colesevelam. Monitor blood pressure if dosing times cannot be separated.
What other medicines interact with Amlodipine-olmesartan?
MediHelp also lists interactions of Amlodipine-olmesartan with, for example, Aliskiren, Sparsentan, Amifostine. The full list is on the Amlodipine-olmesartan page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
