藥物交互作用
Colesevelam + Gliclazide
嚴重程度: 中度
Colesevelam and Gliclazide: moderate interaction.
最後更新
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摘要
Colesevelam may bind sulfonylureas in the gut and reduce absorption, which can weaken glycemic control. This has been shown with glipizide-type agents and is likely a class effect.
用白話說明這項交互作用的意義
Colesevelam and Gliclazide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Colesevelam belongs to Endocrine; Gliclazide belongs to Endocrine.
為什麼會發生
Bile acid sequestrant binds the sulfonylurea in the gastrointestinal tract, reducing absorption.
處置方式
Give gliclazide at least four hours before colesevelam. Monitor glucose if the dosing schedule changes.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Gliclazide 的其他交互作用
Colesevelam 的其他交互作用
常見問題
Can I take Colesevelam with Gliclazide?
MediHelp rates the interaction as moderate. Colesevelam and Gliclazide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Colesevelam may bind sulfonylureas in the gut and reduce absorption, which can weaken glycemic control. This has been shown with glipizide-type agents and is likely a class effect.
How serious is the interaction between Colesevelam and Gliclazide?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give gliclazide at least four hours before colesevelam. Monitor glucose if the dosing schedule changes.
What other medicines interact with Gliclazide?
MediHelp also lists interactions of Gliclazide with, for example, Ciprofloxacin, Clarithromycin, Disopyramide. The full list is on the Gliclazide page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
