藥物交互作用
Amobarbital + Liothyronine
嚴重程度: 中度
Amobarbital and Liothyronine: moderate interaction.
最後更新
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本頁的臨床內容僅提供英文版。
摘要
Barbiturates can increase the hepatic breakdown of thyroid hormones, potentially lowering effective thyroid hormone levels. Patients on replacement therapy may develop signs of hypothyroidism.
用白話說明這項交互作用的意義
Amobarbital and Liothyronine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Amobarbital belongs to Central Nervous System; Liothyronine belongs to Endocrine.
為什麼會發生
Hepatic enzyme induction increases thyroid hormone metabolism and clearance.
處置方式
Monitor thyroid function tests and clinical status after starting or stopping amobarbital, and adjust the liothyronine dose accordingly.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Amobarbital 的其他交互作用
Liothyronine 的其他交互作用
常見問題
Can I take Amobarbital with Liothyronine?
MediHelp rates the interaction as moderate. Amobarbital and Liothyronine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Barbiturates can increase the hepatic breakdown of thyroid hormones, potentially lowering effective thyroid hormone levels. Patients on replacement therapy may develop signs of hypothyroidism.
How serious is the interaction between Amobarbital and Liothyronine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor thyroid function tests and clinical status after starting or stopping amobarbital, and adjust the liothyronine dose accordingly.
What other medicines interact with Amobarbital?
MediHelp also lists interactions of Amobarbital with, for example, Calcium / magnesium / potassium / sodium oxybates, Doravirine, Elbasvir / grazoprevir. The full list is on the Amobarbital page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
