藥物交互作用
Cholestyramine + Liothyronine
嚴重程度: 中度
Cholestyramine and Liothyronine: moderate interaction.
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摘要
Cholestyramine binds thyroid hormones in the gut and markedly reduces absorption of oral liothyronine. This can cause hypothyroid symptoms and raised TSH.
用白話說明這項交互作用的意義
Cholestyramine and Liothyronine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Cholestyramine belongs to Cardiovascular; Liothyronine belongs to Endocrine.
為什麼會發生
Resin binding of liothyronine in the gastrointestinal tract reduces absorption and may interrupt enterohepatic recirculation.
處置方式
Separate liothyronine from cholestyramine by at least 4 hours. Monitor TSH and adjust the thyroid dose if needed.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Cholestyramine 的其他交互作用
Liothyronine 的其他交互作用
常見問題
Can I take Cholestyramine with Liothyronine?
MediHelp rates the interaction as moderate. Cholestyramine and Liothyronine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Cholestyramine binds thyroid hormones in the gut and markedly reduces absorption of oral liothyronine. This can cause hypothyroid symptoms and raised TSH.
How serious is the interaction between Cholestyramine and Liothyronine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Separate liothyronine from cholestyramine by at least 4 hours. Monitor TSH and adjust the thyroid dose if needed.
What other medicines interact with Cholestyramine?
MediHelp also lists interactions of Cholestyramine with, for example, Cholic acid, Deferasirox, Leflunomide. The full list is on the Cholestyramine page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
