藥物交互作用
Canagliflozin-metformin + Liothyronine
嚴重程度: 中度
Canagliflozin-metformin and Liothyronine: moderate interaction.
最後更新
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摘要
Thyroid hormones can raise blood glucose and increase insulin requirements in diabetes. Starting or increasing liothyronine may reduce the effect of canagliflozin-metformin.
用白話說明這項交互作用的意義
Canagliflozin-metformin and Liothyronine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Canagliflozin-metformin belongs to Endocrine; Liothyronine belongs to Endocrine.
為什麼會發生
Thyroid hormone increases hepatic glucose output, gut glucose absorption and metabolic rate, opposing antidiabetic therapy.
處置方式
Monitor blood glucose when starting or changing the liothyronine dose. Adjust antidiabetic therapy as needed.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Canagliflozin-metformin 的其他交互作用
Liothyronine 的其他交互作用
常見問題
Can I take Canagliflozin-metformin with Liothyronine?
MediHelp rates the interaction as moderate. Canagliflozin-metformin and Liothyronine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Thyroid hormones can raise blood glucose and increase insulin requirements in diabetes. Starting or increasing liothyronine may reduce the effect of canagliflozin-metformin.
How serious is the interaction between Canagliflozin-metformin and Liothyronine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose when starting or changing the liothyronine dose. Adjust antidiabetic therapy as needed.
What other medicines interact with Canagliflozin-metformin?
MediHelp also lists interactions of Canagliflozin-metformin with, for example, Contrast media, Diatrizoate, Diatrizoate meglumine / diatrizoate. The full list is on the Canagliflozin-metformin page.
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