藥物交互作用
Amphotericin b liposomal + Lomustine
嚴重程度: 中度
Amphotericin b liposomal and Lomustine: moderate interaction.
最後更新
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摘要
Amphotericin B can cause kidney injury and infusion reactions, while lomustine causes myelosuppression and may add to toxicity. The extent of any true interaction is poorly defined.
用白話說明這項交互作用的意義
Amphotericin b liposomal and Lomustine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Amphotericin b liposomal belongs to Anti Fungals; Lomustine belongs to Oncology.
為什麼會發生
Mechanism not established; possible additive renal and hematologic toxicity.
處置方式
Monitor renal function, electrolytes and blood counts, and observe for hypotension or bronchospasm during infusions.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Lomustine 的其他交互作用
- Adenovirus types 4 and 7 live + Lomustine 禁忌併用
- Bcg vaccine live + Lomustine 禁忌併用
- Influenza virus vaccine quadrivalent intranasal + Lomustine 禁忌併用
- Lomustine + Measles mumps and rubella vaccine 禁忌併用
- Lomustine + Measles mumps and rubella vaccine live 禁忌併用
- Lomustine + Measles mumps rubella and varicella vaccine live 禁忌併用
Amphotericin b liposomal 的其他交互作用
常見問題
Can I take Amphotericin b liposomal with Lomustine?
MediHelp rates the interaction as moderate. Amphotericin b liposomal and Lomustine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Amphotericin B can cause kidney injury and infusion reactions, while lomustine causes myelosuppression and may add to toxicity. The extent of any true interaction is poorly defined.
How serious is the interaction between Amphotericin b liposomal and Lomustine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor renal function, electrolytes and blood counts, and observe for hypotension or bronchospasm during infusions.
What other medicines interact with Lomustine?
MediHelp also lists interactions of Lomustine with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal. The full list is on the Lomustine page.
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